4 Results for "

Euphorbia fischeriana Steud.

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Euphorbia fischeriana Steud." in MCE Product Catalog:

1
Jolkinolide B
Jolkinolide B
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1 Cited Publications
Art. -Nr.: HY-N0732
CAS. Nr.: 37905-08-1
Category:  

Euphorbia fischeriana Steud. Terpenoids Euphorbiaceae Diterpenoids Plants Disease Research Fields Cancer

Target:  

IAP Akt Caspase NF-κB TGF-beta/Smad JAK Bacterial Apoptosis

Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis .
Jolkinolide A
Jolkinolide A
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Art. -Nr.: HY-119767
CAS. Nr.: 37905-07-0
Category:  

Euphorbia fischeriana Steud. Terpenoids Euphorbiaceae Diterpenoids Plants

Target:  

VEGFR Apoptosis

Jolkinolide A is a diterpenoid, can be extracted from the roots of Euphorbia fischeriana Steud. Jolkinolide A exhibits anti-tumor activity, by affecting on angiogenesis of tumor tissues. Jolkinolide A significantly inhibits the Akt-STAT3-mTOR signaling pathway and reduces the expression of VEGF in A549 cells .
Jolkinolide B (Standard)
Jolkinolide B (Standard)
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Art. -Nr.: HY-N0732R
CAS. Nr.: 37905-08-1
Category:  

Euphorbia fischeriana Steud. Terpenoids Euphorbiaceae Diterpenoids Plants

Target:  

Reference Standards IAP Akt Caspase NF-κB TGF-beta/Smad JAK Bacterial Apoptosis

Jolkinolide B (Standard) is the analytical standard of Jolkinolide B (HY-N0732). This product is intended for research and analytical applications. Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis .
17-Hydroxyjolkinolide B
17-Hydroxyjolkinolide B
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Art. -Nr.: HY-N19376
CAS. Nr.: 247037-88-3
Category:  

Euphorbia fischeriana Steud. Terpenoids Euphorbiaceae Diterpenoids Plants

Target:  

Others

17-Hydroxyjolkinolide B is a diterpenoid found in Euphorbia fischeriana Steud. 17-Hydroxyjolkinolide B exhibits bioactivities .
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